2,3,5,6-Di-O-isopropylidene-α-D-mannofuranose Cas:14131-84-1 White to Almost White Crystalline Powder
| Catalog Number | XD90028 |
| Product Name | 2,3,5,6-Di-O-isopropylidene-α-D-mannofuranose |
| CAS | 14131-84-1 |
| Molecular Formula | C12H20O6 |
| Molecular Weight | 260.28 |
| Storage Details | 2 to 8 °C |
| Harmonized Tariff Code | 2932999099 |
Product Specification
| Appearance | White to almost white crystalline powder |
| Density | 1.214 |
| Melting point | 125-126 °C |
| Boiling point | 359.3 °C at 760 mmHg |
| Refractive index | 24 ° |
| Flash point | 171.1 °C |
| Specific rotation | 21 º |
| Assay | 99% |
Protected mannose intermediate used in the syntheses of ovalicin and of the sugar core of hikizimycin.
A series of 2-methyl-N-substituted-benzimidazoles, bearing hydroxypyrrolidinon-5-yl or hydroxypyrrolidin-2-yl, 2,3:5,6-di-O-isopropylidene-alpha-D-mannofuranoside, 2,3,5,6-tetrahydroxy-alpha-D-mannofuranoside, 1:2,5:6-di-O-isopropylidene-alpha-D-gluco-furanose,3-O-benzyl-6,7-dideoxy-1:2-O-isopropylidene-alpha-D-xylo-heptofuranos-5-ulose, 3-O-benzyl-6,7-dideoxy-1,2-dihydroxy-alpha-D-xylo-heptofuranos-5-ulose, 1,2,5,6-tetrahydroxy-alpha-D-glucofuranose sugar moieties, were obtained in good yields from 2-methyl N-(trichloroacetamidomethyl)benzimidazole as a donor and carbohydrate residues as acceptor precursors in the presence of catalytic amount of trimethylsilyl trifluoromethanesulfonate (TMSOTf) as Lewis acid. Compounds 6, 7, 10, 13, 15, and 16 showed significant anti-inflammatory and analgesic activities.
