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Glucose-pentaacetate Cas: 604-68-2 White Powder 99% Pentaacetate Pentaacetyl-alpha-D-glucose

Short Description:

Catalog Number: XD90033
Cas: 604-68-2
Molecular Formula: C16H22O11
Molecular Weight: 390.34
Availability: In Stock
Price:
Prepack: 100g USD20
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Product Detail

Product Tags

Catalog Number: XD90033
Product Name Glucose-pentaacetate
CAS 604-68-2
Molecular Formula C16H22O11
Molecular Weight 390.34
Storage Details Ambient
Harmonized Tariff Code 29400000

Product Specification

Arsenic 0.5%max
Loss on Drying ≤ 0.5%
Assay 99%Min
Specific optical rotation +100 to +103
MP 111 to 114°C
Appearance White powder
Heavy Metal 20ppm max
Ignition residue 0.1%max

In the presence of 2.8 mM D-glucose, beta-D-glucose pentaacetate (1. 7 mM) augmented insulin release from isolated rat pancreatic islets more than alpha-D-glucose pentaacetate. Likewise, the further increment in insulin output evoked by nateglinide (0.01 mM) was higher in islets exposed to beta- rather than alpha-D-glucose pentaacetate. Inversely, in the presence of 2.8 mM unesterified D-glucose, alpha-L-glucose pentaacetate, but not beta-L-glucose pentaacetate, significantly augmented insulin output. The higher insulinotropic potency of the beta-anomer of D-glucose pentaacetate coincided with the fact that it significantly increased the paired ratio between D-[U-14C]glucose oxidation and D-[5-3H]glucose utilization, whereas alpha-D-glucose pentaacetate failed to do so. These findings are interpreted to support the concept that the stimulation of insulin release by these esters is largely attributable to their direct interaction with a stereospecific receptor, with preference for the configuration of the C1 common to beta-D-glucose pentaacetate and alpha-L-glucose pentaacetate.


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    Glucose-pentaacetate Cas: 604-68-2 White Powder 99% Pentaacetate Pentaacetyl-alpha-D-glucose