Methyl 1,2,3,4-tetra-O-acetyl-B-D-glucuronate Cas:7355-18-2 98%
| Catalog Number | XD90029 |
| Product Name | methyl 1,2,3,4-tetra-O-acetyl-B-D-glucuronate |
| CAS | 7355-18-2 |
| Molecular Formula | C15H20O11 |
| Molecular Weight | 376.31 |
| Storage Details | 2-8 °C |
| Harmonized Tariff Code | 29389090 |
Product Specification
| Appearance | White to Almost white powder to crystal |
| Assay | 98% |
Methyl 1,2,3,4-tetra-O-acetyl-β-D-glucuronate has been used in a study to assess design and synthesis of a water-soluble glucuronide derivatives of camptothecin for cancer prodrμg monotherapy and antibody-directed enzyme prodrμg therapy. It has also been used in a study to investigate the synthesis and role of glycosylthio heterocycles in carbohydrate chemistry.
Synthesis of derivatives of pentopyranic acid
N4-Benzoylcytosine 1-(methyl 2,3,4-tri-O-acetyl-β-D-glucopyranosiduronate) has been obtained with a yield of 70% by the glycosylation of the trimethylsilyl derivative of N4-benzoylcytosine with methyl 1,2,3,4-tetra-O-acetyl-β-D-glucopyranuronate in the presence of three equivalents of SnCl4 as condensing agent. Cytosine 1-(β-D-glucopyranosiduronamide) (IV) — the amide of pentopyranic acid — has been synthesized in practically quantitative yield by the ammonolysis of the nucleoside (I).
