S)-(+)-Camptothecin Cas: 7689-03-4
| Catalog Number | XD92150 |
| Product Name | S)-(+)-Camptothecin |
| CAS | 7689-03-4 |
| Molecular Formula | C20H16N2O4 |
| Molecular Weight | 348.35 |
| Storage Details | 2-8°C |
| Harmonized Tariff Code | 29397990 |
Product Specification
| Appearance | Off-white to pale yellow powder |
| Assay | 99% min |
| Melting Point | 261 - 265 Deg C |
| Specific rotation | +29 to +31 |
| Loss on Drying | 1% max |
| Purity HPLC | >99% |
1. Anticancer drugs. For gastric cancer, colon cancer, rectal cancer, head and neck cylindroid cancer and bladder cancer
2. For the treatment of gastric cancer, intestinal cancer, chronic granulocytic type and acute leukemia, etc.
3. Irreversibly binds to the DNA topoisomerase I complex, affecting the cell cycle process
4. Camptothecin was originally isolated from the stems of Camptotheca acuminata and showed anti-leukemia/anti-tumor activity. It irreversibly binds to the DNA topoisomerase I complex, inhibits DNA recombination after topoisomerase I shearing, and locks the enzyme and DNA in the form of a covalent bond.
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