Tiamulin fumarate Cas: 55297-96-6
| Catalog Number | XD92379 |
| Product Name | Tiamulin fumarate |
| CAS | 55297-96-6 |
| Molecular Formula | C32H51NO8S |
| Molecular Weight | 609.82 |
| Storage Details | 2 to 8 °C |
| Harmonized Tariff Code | 29419000 |
Product Specification
| Appearance | White/ off white powder |
| Assay | 99% min |
| Melting Point | 143 - 149°C |
| Heavy metals | <10ppm |
| pH | 3.1 - 4.1 |
| Loss on Drying | <0.5% |
| Solubility | Soluble in water, freely soluble in anhydrous ethanol and soluble in methanol |
| Optical Rotation | +24 to +28 |
| Residue on Ignition | <0.1% |
| Total Impurities | <2% |
| Water Content (KF) | ≤ 4.0% |
Tiamulin is a semi–synthetic analogue of pleuromutilin in which the hydroxyacetyl side chain is replaced with a larger diethylaminoethylthioacetyl moiety, providing greater hydrophobicity. The hemi-fumarate provides a stable salt with improved water solubility. Tiamulin is a potent and highly selective antibiotic active against a range of Gram positive bacteria, with no cross resistance to existing antibiotic classes due to its unique mode of action of inhibiting protein synthesis by binding to domain V of 23S rRNA.
Close
