Platinum(IV) chloride Cas:13454-96-1 Red-brown Powder
| Catalog Number | XD90688 |
| Product Name | Platinum(IV) chloride |
|
CAS |
13454-96-1 |
|
Molecular Formula |
Cl4Pt |
|
Molecular Weight |
336.89 |
| Storage Details | Store below +30°C |
| Harmonized Tariff Code | 28439090 |
Product Specification
| Appearance | Red-brown Powder |
| Assay | 99% |
| Density | 4.303 |
| Melting point | 370℃ |
| logP | 2.75550 |
To construct a drug carrier and gene vector PEG-PEI-Pt.Polyethyleneglycol (PEG) was coupled to polyethylenimine (PEI 600) and platinum tetrachloride; PEG-PEI-Pt complex was formed in ethanol. The complex was characterized by XRD, UV-VIS and FT-IR and the DNA condensation was tested by electrophoretic mobility shift assay. The cell viability was evaluated by MTT assay in Hela, B16, A293 and COS-7 cells and in vitro transfection efficiency was measured in A293 and B16 cells.The structure of PEG-PEI-Pt was characterized by XRD, UV-VIS and FT-IR. PEG-PEI-Pt complex was able to bind DNA at N/P weight ratio of 0.4:1; the complex showed cytotoxicity on Hela and B16 cells. The complex had higher transfection efficiency in A293 and B16 cells than PEI 600.A novel drug carrier and gene vector PEG-PEI-Pt was constructed successfully.
