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Pemetrexed disodium is an antineoplastic (anti-cancer) medication that is primarily used in the treatment of certain types of cancer, particularly non-small cell lung cancer (NSCLC) and malignant pleural mesothelioma. It is typically prescribed by oncologists and administered intravenously in a healthcare setting.For patients with non-small cell lung cancer, pemetrexed disodium is often used in combination with cisplatin as a first-line treatment for advanced or metastatic disease. It can also be used as a maintenance treatment following initial chemotherapy. Pemetrexed disodium works by inhibiting the activity of several enzymes involved in the synthesis of DNA and RNA, which are required for cancer cell growth and division. By interfering with these processes, the drug helps to slow down or stop the growth of cancer cells.In the case of malignant pleural mesothelioma, pemetrexed disodium is typically combined with cisplatin and administered after surgery, if applicable. This combination therapy has been shown to improve overall survival in patients with this aggressive form of cancer. Pemetrexed disodium works by targeting and inhibiting certain enzymes that are important for cell division and growth, thereby reducing the spread and growth of cancer cells in the body.While pemetrexed disodium is effective in treating cancer, it can also cause side effects. Common side effects include fatigue, nausea, vomiting, loss of appetite, diarrhea, constipation, rash, and hair loss. Some patients may experience changes in blood cell counts, which can increase the risk of infections and bleeding. However, it is important to note that not all patients will experience these side effects, and their intensity and duration can vary from person to person. Your healthcare provider will monitor your blood counts and provide supportive care, such as anti-nausea medications or growth factor injections, to manage these side effects.It is crucial to follow the instructions and guidance of your healthcare provider when using pemetrexed disodium. They will determine the appropriate dosage, frequency, and duration of treatment based on your specific cancer type, stage, and overall health. They can also provide personalized advice and support in managing any side effects or concerns that may arise throughout your treatment journey.