Geldanamycin Cas: 30562-34-6
| Catalog Number | XD92264 |
| Product Name | Geldanamycin |
| CAS | 30562-34-6 |
| Molecular Formula | C29H40N2O9 |
| Molecular Weight | 560.64 |
| Storage Details | -15 to -20 °C |
| Harmonized Tariff Code | 29419000 EXP 2941900000 IMP |
Product Specification
| Appearance | Yellow powder |
| Assay | 99% min |
Geldanamycin is a potent antitumor antibiotic active at nanomolar concentration against 60 cell lines. It binds specifically to the heat shock protein Hsp90 and to its endoplasmic reticulum homologue GP96, and thus interferes with conformational maturation of proteins and the cellular stress response. In addition, it is a potent inhibitor of the nuclear hormone receptor family.
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