Cyclosporin A CAS:59865-13-3 White crystalline powder 99%
| Catalog Number | XD90346 |
| Product Name | Cyclosporin A |
| CAS | 59865-13-3 |
| Molecular Formula | C62H111N11O12 |
| Molecular Weight | 1202.61 |
| Storage Details | 2 to 8 °C |
| Harmonized Tariff Code | 29419000 |
Product Specification
| Assay | 99% |
| Appearance | White crystalline powder |
| Grade | USP 35 |
| Impurity | Total impurities:0.6% max, Max Single Impurities: 0.2% |
| Heavy metals | 20ppm max |
| Acetone | 10ppm |
| Loss on Drying | 2.0% max |
| Storage Temperature | +4% |
| Appearance of Solution | Solution as per specification in EPIV |
| Petroleum ether soluble substances | 31ppm |
Properties: White or off-white powder, odorless and tasteless. It is easily soluble in methanol, ethanol or acetonitrile, easily soluble in ethyl acetate, soluble in acetone or ether, and almost insoluble in water. The specific rotation of this product is determined by chemical book, and dissolved in methanol to make a solution containing 10 mg per 1 ml. The specific rotation is -182° to -192°. Uses: biochemical research. Inhibition of T cell receptor signaling pathways
This product is a new type of immunosuppressant. It is a cyclic polypeptide substance composed of eleven amino acids. It suppresses humoral and cell-delivered immune functions without suppressing the bone marrow and reducing the number of white blood cells. Can prevent the rejection of the transplanted tissue or organ Chemicalbook. It is clinically used for kidney transplantation, liver, lung and heart transplantation. In addition, it has a certain curative effect on autoimmune diseases, as well as schistosomiasis, malaria, diabetes, AIDS, etc., as well as anti-inflammatory properties.
For the treatment of leukemia, cancer, kidney transplantation, tuberculosis, etc.
