Novobiocin sodium salt Cas: 1476-53-5
| Catalog Number | XD92307 |
| Product Name | Novobiocin sodium salt |
| CAS | 1476-53-5 |
| Molecular Formula | C31H35N2NaO11 |
| Molecular Weight | 634.61 |
| Storage Details | 2-8°C |
| Harmonized Tariff Code | 29419000 |
Product Specification
| Appearance | White to off-white crystalline powder |
| Assay | 99% min |
| Colour in solution | <0.4 |
| Impurities Total | <12.0% |
| Novobiocin As Is Average HPLC Normal | >845ug/mg |
| Novobiocin Dried Basis HPLC Normal | >850ug/mg |
| Specific Rotation Dried Basis | -58 to -50° |
| pH | 6.5 - 8.5 |
| Loss On Drying | <6.0% |
| Residue On Ignition Dried Basis | 10.5 - 12.0% |
| Acetone | <5000ppm |
| Methanol | <3000ppm |
| Heptane | <5000ppm |
| Isooctane | <5000ppm |
| Residual Novobiocin Acid | <2.0% |
| Microcount Bacteria | <100cfu/g |
| Microcount Fungi | <10cfu/g |
| Residual Solvents Total | <27000ppm |
| Novobiocin-2,3-Carbonate | <0.5% |
| Unknown B (RRT approx. 0.3) | <0.5% |
| Decarbamyl Novobiocin | <6.0% |
| Impurities unspecified | <1.0% |
| Isonovobiocin | <4.0% |
Novobiocin sodium salt is an effective antistaphylococcal agent used in the treatment of Methicillin-resistant Staphylococcus aureus (MRSA). It is also used to inhibit the activity of retroviral RNA-dependent DNA polymerase as well as inhibitor of bacterial DNA gyrase and eukaryotic DNA topoisomerase.
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