Iodoacetamide Cas: 144-48-9 98% White to yellow solid
| Catalog Number | XD90247 |
|
Product Name |
Iodoacetamide |
|
CAS |
144-48-9 |
|
Molecular Formula |
C2H4INO |
|
Molecular Weight |
184.96 |
| Storage Details | Ambient |
|
Harmonized Tariff Code |
29241900 |
Product Specification
| Loss on Drying | <1% |
| Assay | ≥98% |
| Nitrogen | 7.2 - 7.8% |
| Appearance | White to yellow solid |
| Solubility in methanol | Almost transparency |
| Elemental Analysis Carbon |
12.5 - 13.2% |
α-Iodoacetamide is a compound used as an electrophile for covalent modification of nucleophilic residues on proteins (cysteine, methionine, histidine). When modifying the active-site residues of cysteine proteases, α-Iodoacetamide acts as an irreversible inhibitor of these enzymes.
Uses: It can be used as a protease inhibitor CH2ICONH2. Like iodoacetic acid, it can irreversibly inhibit SH enzymes through the following reactions. R-SH+ICH2CONH2→R-S-CH2CONH2+HI
Uses: Alkylation reagents for histidine and cysteine in proteomics, for peptide sequencing and enzyme inhibitors. Also used in organic synthesis.
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