Europe style for Oncology - Glutathione reduced Cas: 70-18-8 98-101% Clear and colourless – XD BIOCHEM
Europe style for Oncology - Glutathione reduced Cas: 70-18-8 98-101% Clear and colourless – XD BIOCHEM Detail:
| Catalog Number | XD90284 |
| Product Name | Glutathione reduced |
|
CAS |
70-18-8 |
|
Molecular Formula |
C10H17N3O6S |
|
Molecular Weight |
307.32 |
| Storage Details | 2 to 8 °C |
|
Harmonized Tariff Code |
29309098 |
Product Specification
| Assay | 98% – 101% |
| Appearance | White crystalline powder |
| Grade | EP 7.0 |
| Impurity A | <0.5% |
| Impurity B | <0.5% |
| Heavy metals | <10ppm |
| Bacterial endotoxin | <0.10EU/mg |
| Impurity C | <1.5% |
| Impurity D | <1.0% |
| Loss on Drying | <0.5% |
|
Solubility |
Freely soluble in water, slightly soluble in ethanol and methylene chloride |
| Iron | <10ppm |
| Chlorides | <200ppm |
| Appearance of Solution | Clear and colourless |
| Specific optical rotation | -15.5 to -17.5 |
| Total Impurities | <2.5% |
| Ammonium | <200ppm |
| Sulfated ash | <0.1% |
| Sulphates | <300ppm |
| Impurity E | <0.5% |
Post-translational protein modifications, such as tyrosine phosphorylation, regulate protein-protein interactions (PPIs) critical for signal processing and cellular phenotypes. We extended an established yeast two-hybrid system employing human protein kinases for the analyses of phospho-tyrosine (pY)-dependent PPIs in a direct experimental, large-scale approach. We identified 292 mostly novel pY-dependent PPIs which showed high specificity with respect to kinases and interacting proteins and validated a large fraction in co-immunoprecipitation experiments from mammalian cells. About one-sixth of the interactions are mediated by known linear sequence binding motifs while the majority of pY-PPIs are mediated by other linear epitopes or governed by alternative recognition modes. Network analysis revealed that pY-mediated recognition events are tied to a highly connected protein module dedicated to signaling and cell growth pathways related to cancer. Using binding assays, protein compleme ntation and phenotypic readouts to characterize the pY-dependent interactions of TSPAN2 (tetraspanin 2) and GRB2 or PIK3R3 (p55γ), we exemplarily provide evidence that the two pY-dependent PPIs dictate cellular cancer phenotypes.
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The client satisfaction is our primary concentrate on. We uphold a consistent level of professionalism, top quality, credibility and service for Europe style for Oncology - Glutathione reduced Cas: 70-18-8 98-101% Clear and colourless – XD BIOCHEM , The product will supply to all over the world, such as: Macedonia, United Arab Emirates, Iraq, Look forward to the future, we will focus more on the brand building and promotion . And in the process of our brand global strategic layout we welcome more and more partners join us, work together with us based on mutual benefit. Let's develop market by fully utilizing our comprehensive advantages and strive for building.
By Claire from Mauritius - 2017.10.27 12:12
Good quality and fast delivery, it's very nice. Some products have a little bit problem, but the supplier replaced timely, overall, we are satisfied.
By Lulu from Denver - 2017.10.13 10:47
