page_banner

Products

Erythromycin CAS:114-07-8 99% White crystalline powder

Short Description:

Catalog Number: XD90353
CAS: 114-07-8
Molecular Formula: C37H67NO13
Molecular Weight: 733.93
Availability: In Stock
Price:  
Prepack: 5g USD10
Bulk Pack: Request Quote

 

 

 

 

 


Product Detail

Product Tags

Catalog Number XD90353
Product Name Erythromycin
CAS 114-07-8
Molecular Formula C37H67NO13
Molecular Weight 733.93
Storage Details Ambient
Harmonized Tariff Code 29415000

 

Product Specification

Identification IR absorption spectrum comparison with USP RS
Water 10% max
Ethanol 0.5% max
Residue on Ignition 0.2% max
Assay 99%
Specific rotation -71 ° to -78 °
Appearance White crystalline powder
Crystallinity Meets the requirements
Erythromycin B 12.0% max
Erythromycin C 5.0% max
Limit of thiocyanate 0.3% max
Propanol 0.5% max
N-butyl acetate 0.5% max
Erythromycin A enol ether 0.3% max
Any individual related substastances 3.0% max

 

In the present study, we examined the interaction of antimicrobial agents with four model lipid membranes that mimicked mammalian cell membranes and Gram-positive and -negative bacterial membranes and analyzed the binding kinetics using our surface plasmon resonance (SPR) technique. The selective and specific binding characteristics of antimicrobial agents to the lipid membranes were estimated, and the kinetic parameters were analyzed by application of a two-state reaction model. Reproducible analysis of binding kinetics was observed. Vancomyicn, teicoplanin, erythromycin, and linezolid showed little interaction with the four lipid membranes in the SPR system. On the other hand, vancomycin analogues showed interaction with the model lipid membranes in the SPR system. The selective and specific binding characteristics of vancomycin analogues to the lipid membranes are discussed based on data for in vitro antibacterial activities and our data on the binding affinity of the D-alanyl-D-ala nine terminus of a pentapeptide cell wall obtained by SPR. The mechanism of antibacterial activity against Staphylococcus aureus and vancomycin-resistant enterococci could be evaluated using the binding affinity obtained with our SPR techniques. The results indicate that the SPR method could be widely applied to predict binding characteristics, such as selectivity and specificity, of many antimicrobial agents to lipid membranes.


  • Previous:
  • Next:

  • Close

    Erythromycin CAS:114-07-8 99% White crystalline powder