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BETA-NADPH TETRA(CYCLOHEXYLAMMONIUM) SALT Cas: 100929-71-3

Short Description:

Catalog Number: XD90431
Cas: 100929-71-3
Molecular Formula: C21H30N7O17P3.4[C6H13N]
Molecular Weight: 1142.11748
Availability: In Stock
Price:  
Prepack: 5g USD20
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Product Detail

Product Tags

Catalog Number XD90431
Product Name BETA-NADPH TETRA(CYCLOHEXYLAMMONIUM) SALT

CAS

100929-71-3

Molecular Formula

C21H30N7O17P3.4[C6H13N]

Molecular Weight

1142.11748
Storage Details -20 °C

 

Product Specification

Appearance White powder
Assay 99%

 

NADPH oxidases are a family of enzymes that generate reactive oxygen species (ROS). The NOX1 (NADPH oxidase 1) and NOX2 oxidases are the major sources of ROS in the artery wall in conditions such as hypertension, hypercholesterolaemia, diabetes and ageing, and so they are important contributors to the oxidative stress, endothelial dysfunction and vascular inflammation that underlies arterial remodelling and atherogenesis. In this Review, we advance the concept that compared to the use of conventional antioxidants, inhibiting NOX1 and NOX2 oxidases is a superior approach for combating oxidative stress. We briefly describe some common and emerging putative NADPH oxidase inhibitors. In addition, we highlight the crucial role of the NADPH oxidase regulatory subunit, p47phox, in the activity of vascular NOX1 and NOX2 oxidases, and suggest how a better understanding of its specific molecular interactions may enable the development of novel isoform-selective drugs to prevent or treat cardiova scular diseases.


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    BETA-NADPH TETRA(CYCLOHEXYLAMMONIUM) SALT Cas: 100929-71-3