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2-(3,5-Dimethyl-4-(2-(pyrrolidin-1-yl)ethoxy)phenyl)-5,7-dimethoxyquinazolin-4(3H)-one Cas:1044871-04-6

Short Description:

Catalog Number: XD90961
Cas: 1044871-04-6
Molecular Formula: C24H29N3O4
Molecular Weight: 423.5
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Product Detail

Product Tags

Catalog Number XD90961
Product Name 2-(3,5-Dimethyl-4-(2-(pyrrolidin-1-yl)ethoxy)phenyl)-5,7-dimethoxyquinazolin-4(3H)-one

CAS

1044871-04-6

Molecular Formula

C24H29N3O4

Molecular Weight

423.5
Storage Details  
Harmonized Tariff Code  

 

Product Specification

Appearance  
Assay  
Boiling point 612.6±65.0 °C(Predicted)
Density 1.25±0.1 g/cm3(Predicted)
Acidity coefficient (pKa)9.54±0.20(Predicted)

 

RVX-297 is a highly potent, orally active BET inhibitor selective for BD2. The IC50s of RVX-297 for BRD2(BD2), BRD3(BD2), and BRD4(BD2) were 0.08, 0.05, and 0.02 μM, respectively. RVX-297 inhibits the expression of various immune cell inflammatory genes. Efficacy of RVX-297 in preclinical models of acute inflammation and autoimmunity.


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    2-(3,5-Dimethyl-4-(2-(pyrrolidin-1-yl)ethoxy)phenyl)-5,7-dimethoxyquinazolin-4(3H)-one Cas:1044871-04-6